Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDE3B All Species: 10
Human Site: T625 Identified Species: 20
UniProt: Q13370 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13370 NP_000913.2 1112 124333 T625 E T Q Q E E E T E K K D S R K
Chimpanzee Pan troglodytes XP_520783 1141 125048 N628 V T S D Y E T N N N S D S S D
Rhesus Macaque Macaca mulatta XP_001092891 1117 125088 T625 E T Q Q E E K T E K K D S R K
Dog Lupus familis XP_854529 779 87136 R357 K M G E K S G R I L S Q V M Y
Cat Felis silvestris
Mouse Mus musculus Q61409 1100 122135 E601 L N I V E T Q E E E T M K K A
Rat Rattus norvegicus Q63085 1108 123088 E607 L N I V E T Q E E E T V K E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518516 340 38206
Chicken Gallus gallus NP_001026353 1105 121291 G613 S G E V G S S G L S K E P F H
Frog Xenopus laevis NP_001088828 985 108702 T563 I F D L V E R T G G K S G R I
Zebra Danio Brachydanio rerio XP_691883 1107 124050 S603 E N L I R E E S L E A E S Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q8I0P7 625 69850 L203 H E T P V D L L R K I S V S R
Sea Urchin Strong. purpuratus XP_793920 1558 171759 T989 V T I S E H A T I I E E G M A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42 96.7 60.6 N.A. 81.5 80.6 N.A. 22.4 63.6 59.7 63.2 N.A. N.A. N.A. 26.5 28.2
Protein Similarity: 100 58.2 98.2 64.5 N.A. 86.9 86.7 N.A. 26.9 75 70.8 75.5 N.A. N.A. N.A. 38.2 41.8
P-Site Identity: 100 26.6 93.3 0 N.A. 13.3 13.3 N.A. 0 6.6 26.6 26.6 N.A. N.A. N.A. 6.6 20
P-Site Similarity: 100 26.6 100 20 N.A. 33.3 26.6 N.A. 0 20 26.6 60 N.A. N.A. N.A. 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 9 0 9 0 0 0 0 0 25 0 0 17 % D
% Glu: 25 9 9 9 42 42 17 17 34 25 9 25 0 9 9 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 9 9 0 9 0 9 9 9 9 0 0 17 0 0 % G
% His: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % H
% Ile: 9 0 25 9 0 0 0 0 17 9 9 0 0 0 9 % I
% Lys: 9 0 0 0 9 0 9 0 0 25 34 0 17 9 17 % K
% Leu: 17 0 9 9 0 0 9 9 17 9 0 0 0 0 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 9 0 17 0 % M
% Asn: 0 25 0 0 0 0 0 9 9 9 0 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 17 17 0 0 17 0 0 0 0 9 0 9 0 % Q
% Arg: 0 0 0 0 9 0 9 9 9 0 0 0 0 25 9 % R
% Ser: 9 0 9 9 0 17 9 9 0 9 17 17 34 17 0 % S
% Thr: 0 34 9 0 0 17 9 34 0 0 17 0 0 0 0 % T
% Val: 17 0 0 25 17 0 0 0 0 0 0 9 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _